Norma Rosario Flores Holguín

Educación

Áreas de Interés

Últimas publicaciones

• Marine Toxins as Pharmaceutical Treasure Troves: A Focus on Saxitoxin Derivatives from a Computational Point of View

  Norma Flores-Holguín, Joan Sebastian Salas-Leiva, Julián Núñez-Vázquez, Erick Tovar-Ramírez, Daniel Glossman-Mitnik
  MOLECULES, Vol.29. No.. pp275 (2024)

• Investigating the Chemical Reactivity of Kahalalides: A Promising Source of Therapeutic Peptides from Marine Natural Products Using Conceptual Density Functional Theory

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  CHEMISTRYSELECT, Vol.8. No.42. ppe202303207 (2023)

• Molecular Insights into the In Silico Discovery of Corilagin from Terminalia chebula as a Potential Dual Inhibitor of the SARS-CoV-2 Structural Protein

  Sushma Pradeep, Shashank M Patil, Chandan Dharmashekara, Anisha S Jain, Ramith Ramu, Prithvi S Shirahatti, Subhankar P Mandal, Pruthvish Reddy, Chandrashekar Srinivasa, Shranagouda S Patil, Joaquín Ortega-Castro, Juan Frau, Norma Flores-Holguín, Chandan Shivamallu, Shiva Prasad Kollur, Daniel Glossman-Mitnik
  JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, Vol.41. No.20. pp10869-10884 (2023)

• Exploring Marine Toxins: Comparative Analysis of Chemical Reactivity Properties and Potential for Drug Discovery

  Norma Flores-Holguín, Joan Sebastian Salas-Leiva, Erick Núñez-Vázquez, Dariel Tovar-Ramírez, Daniel Glossman-Mitnik
  FRONTIERS IN CHEMISTRY, Vol.11. No.1286804 . pp1-14 (2023)

• Computational Discovery of Marine Molecules of the Cyclopeptide Family with Therapeutic Potential

  Norma Flores-Holguín, Joan S. Salas-Leiva, Daniel Glossman-Mitnik
  PHARMACEUTICALS, Vol.16. No.1377. pp1-20 (2023)

• Understanding the Chemical Reactivity and Biological Properties of Patellamides using Theoretical and Computational Methods

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  COMPUTATIONAL AND THEORETICAL CHEMISTRY, Vol.1229. No.114329. pp1-10 (2023)

• Talarolide A and Talaropeptides A–D: Potential Marine-Derived Therapeutic Peptides with Interesting Chemistry and Biological Activity Studied through Density Functional Theory (DFT) and Conceptual DFT

  Norma Flores-Holguín, Joan S. Salas-Leiva, Daniel Glossman-Mitnik
  MOLECULES, Vol.28. No.6708. pp1-12 (2023)

• Computational Chemistry and Molecular Modeling Techniques for the Study of Micropeptin EI-964: Insights into its Chemical Reactivity and Potential Pharmaceutical Properties

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  Computational Molecular Bioscience, Vol.13. No.3. pp35-47 (2023)

• Exploring the Potential and Limitations of Cyclopeptides as Pharmaceutical Drugs: A Computational Peptidology Approach to the Study of Grassypeptolides A-G

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  THEORETICAL CHEMISTRY ACCOUNTS, Vol.142. No.. pp88 (2023)

• CDFT-Based Chemical Reactivity Properties Analysis of the Fluorine Substitution in the Selective Estrogen Receptor Modulator (SERM) Tamoxifen

  Norma Flores-Holguín, Daniel Glossman-Mitnik
  THEORETICAL CHEMISTRY ACCOUNTS, Vol.142. No.. pp79 (2023)

• "Synthesis, characterization, molecular structure, NBO analysis, chemical reactivity and first hyperpolarizability of 4–(Benzyloxy)benzaldehyde–3,5–dinitrobenzohydrazone: A combined experimental and theoretical approach"

  Ram Niwas Singh, Riya Singh, Poonam Rawat, Anshu Gautam, Mukesh Kumar, Poonam Bharti, Norma Flores-Holguin
  JOURNAL OF MOLECULAR STRUCTURE, Vol.1293. No.. pp136135 (2023)

• Preliminary Evaluation of Lablab purpureus Phytochemicals for anti-BoHV-1 Activity Using In Vitro and In Silico Approaches

  Smitha S Bhat, Sushma Pradeep, Sharanagouda S Patil, Norma Flores-Holguín, Daniel Glossman-Mitnik, Juan Frau, Sarana Rose Sommano, Nemat Ali, Mohamed Mohany, Chandan Shivamallu, Shashanka K Prasad, Shiva Prasad Kollur
  ACS OMEGA, Vol.8. No.. pp22684-22697 (2023)

• Thermostability improvement of sucrose isomerase PalI NX-5: a comprehensive strategy

  A. J. Sardiña-Peña, L. Ballinas-Casarrubias, T. S. Siqueiros-Cendón, E. A. Espinoza-Sánchez, N. R. Flores-Holguín, B. F. Iglesias-Figueroa, Q. Rascón-Cruz
  BIOTECHNOLOGY LETTERS, Vol.. No.. pp (2023)

• Author Correction: Integrated Approach for Studying Bioactive Compounds from Cladosporium spp. against Estrogen Receptor alpha as Breast Cancer Drug Target

  Satish Anandan, Hittanahallikoppal Gajendramurthy Gowtham, C. S. Shivakumara, Anjana Thampy, Sudarshana Brijesh Singh, Mahadevamurthy Murali, Chandan Shivamallu, Sushma Pradeep, Natarajamurthy Shilpa, Ali A. Shati, Mohammad Y. Alfaifi, Serag Eldin I. Elbehairi, Joaquín Ortega‑Castro, Juan Frau, Norma Flores‑Holguín, Shiva Prasad Kollur, Daniel Glossman‑Mitnik
  SCIENTIFIC REPORTS, Vol.13. No.1. pp2328 (2023)

• Integrated Approaches of Molecular Docking, Molecular Dynamics Simulation and Density Functional Theory (DFT) Studies of Bioactive Compounds from Cladosporium spp. against Estrogen Receptor alpha as a Promising Breast Cancer Drug Target

  Satish Anandan, Hittanahallikoppal Gajendramurthy Gowtham, C.S. Shivakumara, Anjana Thampy, Sudarshana Brijesh Singh, Mahadevamurthy Murali, Chandan Shivamallu, Sushma Pradeep, Natarajamurthy Shilpa, Ali A. Shati, Mohammad Y. Alfaifi, Serag Eldin I. Elbehairi, Joaquín Ortega-Castro, Juan Frau, Norma Flores-Holguín, Shiva Prasad Kollur, Daniel Glossman-Mitnik
  SCIENTIFIC REPORTS, Vol.12. No.22446. pp (2022)

• Exploration of Anti-HIV Phytocompounds against SARS-CoV-2 Main Protease: Structure-based Screening, Molecular Simulation, ADME Analysis and Conceptual DFT Studies

  Mahadevamurthy Murali, Hittanahallikoppal Gajendramurthy Gowtham, Shilpa Natarajamurthy, Hemanth Kumar Naguvanahalli Krishnappa, Ana E. Ledesma, Anisha Jain, Ali A. Shati, Mohammad Y. Alfaifi, Serag Eldin I. Elbehairi, Joaquín Ortega-Castro, Juan Frau, Norma Flores-Holguín, Chandan Shivamallu, Shiva Prasad Kollur, Kestur Nagaraj Amruthesh ,Daniel Glossman-Mitnik
  MOLECULES, Vol.27. No.8288. pp1-16 (2022)

• Correction to: An Insight into Reactivity and Bioactivity Properties of Quorum Sensing Peptides Against PDE10A: A Computational Peptidology Approach

  Bhargav Shreevatsa, Chandan Dharmashekara, Anisha S. Jain, Raghavendra Amachawadi, Raghu Ram Achar, Asad Syed, Chandan Shivamallu, Shiva Prasad Kollur, Juan Frau, Norma Flores-Holguín, Daniel Glossman-Mitnik
  JOURNAL OF MOLECULAR MODELING, Vol.28. No.347. pp1-2 (2022)

• Phytoconstituents of Withania somnifera Unveiled Ashwagandhanolide as a Potential Drug Targeting Breast Cancer: Investigations Through Computational, Molecular Docking and Conceptual DFT Studies

  Hittanahallikoppal Gajendramurthy Gowtham, Mahadevamurthy Murali, Sudharshana Brijesh Singh, Chandan Shivamallu, Sushma Pradeep, C. S. Shivakumar, Satish Anandan, Raghu Ram Achar, Ekaterina Silina, Victor Stupin, Joaquín Ortega-Castro, Juan Frau, Norma Flores-Holguín, Kestur Nagaraj Amruthesh, Shiva Prasad Kollur, Daniel Glossman-Mitnik
  PLOS ONE, Vol.17. No.10. ppe0275432 (2022)

• In Vitro Anticancer Screening, Molecular Docking and Antimicrobial Studies of Triazole-Based Nickel(II) Metal Complexes

  Sachin A. Deodware, Umesh B. Barache, Pratibha C. Dhale, Kundalkesha S. Gaikwad, Chandan Shivamallu, Panchsheela A. Ubale, Ali A. Shati, Mohammad Y. Alfaifi, Serag Eldin I. Elbehairi, Raghu Ram Achar, Ekaterina Silina, Victor Stupin, Juan Frau, Norma Flores-Holguín, Shashikant H. Gaikwad, Shiva Prasad Kollur, Daniel Glossman-Mitnik
  MOLECULES, Vol.27. No.6548. pp1-20 (2022)

• Editorial: Recent Advances, New Perspectives and Applications of Conceptual Density Functional Theory

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  FRONTIERS IN CHEMISTRY, Vol.10. No.1003106. pp1-3 (2022)

• An Insight into Reactivity and Bioactivity Properties of Quorum Sensing Peptides against PDE10A: A Computational Peptidology Approach

  Bhargav Shreevatsa, Chandan Dharmashekara, Anisha S. Jain, Raghavendra Amachawadi, Raghu Ram Achar, Asad Syed, Chandan Shivamallu, Shiva Prasad Kollur, Juan Frau, Norma Flores-Holguín, Daniel Glossman-Mitnik
  JOURNAL OF MOLECULAR MODELING, Vol.28. No.209. pp1-17 (2022)

• Computational Nanochemistry Study of the Alisporivir and Cyclosporin A Antimicrobial Peptides through Conceptual DFT-based Computational Peptidology and Pharmacokinetics

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  Mundo Nano, Vol.15. No.29. pp1e-17e (2022)

• Virtual Prospection of Marine Cyclopeptides as Therapeutics by Means of Conceptual DFT and Computational ADMET

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  PHARMACEUTICALS, Vol.15. No.509. pp1-10 (2022)

• Synthesis, spectroscopic and evaluation of anticancer activity of new hydrazone-containing dipyrromethane using experimental and theoretical approaches

  Anshu Gautam, Poonam Rawat, R.N. Singh, Norma Flores-Holguin
  JOURNAL OF MOLECULAR STRUCTURE, Vol.1260. No.132781. pp1-10 (2022)

• Oxidation Degree of a Cell Membrane Model and its Response to Structural Changes, A Coarse-Grained Molecular Dynamics Approach

  Hugo Aceves-Luna, Daniel Glossman-Mitnik, Norma Flores-Holguín
  JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, Vol.40. No.5. pp1930-1941 (2022)

• N-((1H-Pyrrol-2-yl)methylene)-6-methoxypyridin-3-amine and Its Co(II) and Cu(II) Complexes as Antimicrobial Agents: Chemical Preparation, In Vitro Antimicrobial Evaluation, In Silico Analysis and Computational and Theoretical Chemistry Investigations

  Vinusha H. Mariwamy, Shiva Prasad Kollur, Bindya Shivananda, Muneera Begum, Chandan Shivamallu, Chandan Dharmashekara, Sushma Pradeep, Anisha S. Jain, Shashanka K. Prasad, Asad Syed, Abdallah M. Elgorban, Salim Al-Rejaie, Joaquín Ortega-Castro, Juan Frau, Norma Flores-Holguín, Daniel Glossman-Mitnik
  MOLECULES, Vol.27. No.1436. pp1-21 (2022)

• Conceptual DFT-based Computational Peptidology, Pharmacokinetics Study and ADMET Report of the Veraguamides A–G Family of Marine Natural Drugs

  Norma Flores-Holguín, Joaquín Ortega-Castro, Juan Frau, Daniel Glossman-Mitnik
  MARINE DRUGS, Vol.20. No.97. pp1-14 (2022)

• Computational Peptidology Approach to the Study of the Chemical Reactivity and Bioactivity Properties of Aspergillipeptide D, a Cyclopentapeptide of Marine Origin

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  SCIENTIFIC REPORTS, Vol.12. No.506. pp1-13 (2022)

• Computational Pharmacokinetics Report, ADMET Study and Conceptual DFT-based Estimation of the Chemical Reactivity Properties of the Homophymines Family of Marine Cyclopeptides

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  CHEMISTRYOPEN, Vol.10. No.11. pp1142-1149 (2021)

• Virtual Screening for Potential Phytobioactives as Therapeutic Leads to Inhibit NQO1 for Selective Anticancer Therapy

  Bhargav Shreevatsa, Chandan Dharmashekara, Vikas Halasumane Swamy, Meghana V. Gowda, Raghu Ram Achar, Vivek Hamse Kameshwar, Rajesh Kumar Thimmulappa, Asad Syed, Abdallah M. Elgorban, Norma Flores-Holguín, Salim S. Al-Rejaie, Joaquín Ortega-Castro, Juan Frau, Chandan Shivamallu, Shiva Prasad Kollur, Daniel Glossman-Mitnik
  MOLECULES, Vol.26. No.22. pp6863 (2021)

• An Integrated Molecular Modeling Protocol for Drug Screening Based on Conceptual Density Functional Theory and Chemoinformatics for the Study of Marine Cyclopeptides

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  JOURNAL OF MOLECULAR MODELING, Vol.27. No.314. pp1-9 (2021)

• Synthesis, Computational Pharmacokinetics Report, Conceptual DFT-based Calculations and anti-Acetylcholinesterase Activity of Hydroxyapatite Nanoparticles Derived from Acorus calamus Plant Extract

  Sushma Pradeep, Anisha S Jain, Chandan Dharmashekara, Shashanka Prasad, Nagaraju Akshatha, Raghavendra G Amachawadi, Asad Syed, Abdallah Elgorban, Ali H Bahkali, Joaquín Ortega-Castro, Juan Frau, Norma Flores-Holguin, Chandan Shivamallu, Shiva Prasad Kollur, Daniel Glossman-Mitnik
  FRONTIERS IN CHEMISTRY, Vol.9. No.741037. pp1-18 (2021)

• A CDFT-based Computational Peptidology (CDFT-CP) Study of the Chemical Reactivity and Bioactivity of the Marine-derived Alternaramide Cyclopentadepsipeptide

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  JOURNAL OF CHEMISTRY, Vol.2021. No.2989611. pp11 (2021)

• In Silico Pharmacokinetics, ADMET Study and Conceptual DFT Analysis of Two Plant Cyclopeptides Isolated from Rosaceae as a Computational Peptidology Approach

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  FRONTIERS IN CHEMISTRY, Vol.9. No.708364. pp (2021)

• Chemical Synthesis, in vitro Biological Evaluation and Theoretical Investigations of Transition Metal Complexes Derived from 2-(((5-mercapto-1H-pyrrol-2-yl)imino) methyl)6-methoxyphenol

  Honnalagere Mariswamy Vinusha, Shiva Prasad Kollur, Muneera Begum, Chandan Shivamallu, Ramith Ramu, Prithvi S. Shirahatti, Nagendra Prasad, Ravindra Veerapur, Joaquín Ortega-Castro, Juan Frau, Norma Flores-Holguín, Daniel Glossman-Mitnik
  JOURNAL OF MOLECULAR STRUCTURE, Vol.1244. No.130920. pp1-11 (2021)

• Investigation of Antifungal Properties of Synthetic Dimethyl-4-Bromo-1-(Substituted Benzoyl)Pyrrolo[1,2-a]Quinoline-2,3-Dicarboxylates Analogues: Molecular Docking Studies and CDFT-based Chemical Reactivity Descriptors and Pharmacokinetics Evaluation

  Vijayakumar Uppar, Sandeep Chandrashekharappa, Chandan Shivamallu, Sushma P, Shiva Prasad Kollur, Joaquín Ortega-Castro, Juan Frau, Norma Flores-Holguín, Atiyaparveen I Basarikatti, Mallikarjun Chougala, Mrudula Mohan M, Govindappa Banuprakash, Jayadev, Katharigatta N. Venugopala, B P Nandeshwarappa, Asad Syed, Najat Marraiki, Kiran K Mudnakudu-Nagaraju, Basavaraj Padmashali, Daniel Glossman-Mitnik
  MOLECULES, Vol.26. No.2722. pp1-20 (2021)

• Evaluation of Annona muricata Acetogenins as Potential Anti-SARS-CoV-2 Agents Through Computational Approaches

  Shashanka K. Prasad, Sushma Pradeep, Chandan Shimavallu, Shiva Prasad Kollur, Asad Syed, Najat Marraiki, Chukwuebuka Egbuna, Mihnea-Alexandru Gaman, Olga Kosakowska, William C. Cho, Kingsley Chukwuemeka Patrick-Iwuanyanwu, Joaquín Ortega Castro, Juan Frau, Norma Flores-Holguín, Daniel Glossman-Mitnik
  FRONTIERS IN CHEMISTRY, Vol.8. No.624716. pp1-7 (2021)

• Molecular Docking and Conceptual DFT-based Study of some Potential SARS-CoV-2 Inhibitors

  Norma Flores-Holguín, Daniel Glossman-Mitnik
  SIN REVISTA, Vol.10. No.4. pp111-128 (2020)

• Molecular Docking and Conceptual DFT-Based Study of Some Potential SARS-CoV-2 Inhibitors

  Norma Flores-Holguín, Daniel Glossman-Mitnik
  Computational Molecular Bioscience, Vol.10. No.4. pp111-128 (2020)

• Preparation, Spectroscopic Characterization, Theoretical Investigations, and In Vitro Anticancer Activity of Cd(II), Ni(II), Zn(II), and Cu(II) Complexes of 4(3H)-Quinazolinone-Derived Schiff Base

  Ubale Panchsheela Ashok, Shiva Prasad Kollur, Nishad Anil, Bansode Prakash Arun, Sanjay Namdev Jadhav, Sanjay Sarsamkar, Vasant Baburao Helavi, Asha Srinivasan, Sandeep Kaulage, Ravindra Veerapur, Sarah Al-Rashed, Asad Syed , Joaquín Ortega-Castro, Juan Frau, Norma Flores-Holguín, Daniel Glossman-Mitnik
  MOLECULES, Vol.25. No.24. pp5973 (2020)

• Virtual Screening of Marine Natural Compounds by Means of Chemoinformatics and CDFT-Based Computational Peptidology

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  MARINE DRUGS, Vol.18. No.1-17. pp478 (2020)

• Conceptual DFT-Based Computational Peptidology of Marine Natural Compounds: Discodermins A-H

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  MOLECULES, Vol.25. No.4158. pp1-20 (2020)

• In vitro Anticancer Activity of 4(3H)-Quinazolinone Derived Schiff Base and its Cu(II), Zn(II) and Cd(II) Complexes: Preparation, X-ray Structural, Spectral Characterization and Theoretical Investigations

  Ubale Panchsheela Ashok, Shiva Prasad Kollur, Bansode Prakash Arun, Chavan Sanjay, Karhale Shrikrishna Suresh, Nishad Anil, Helavi Vasant Baburao, Datta Markad, Joaquín Ortega Castro, Juan Frau, Norma Flores-Holguín, Daniel Glossman-Mitnik
  INORGANICA CHIMICA ACTA, Vol.511. No.119846. pp1-10 (2020)

• Influence on the Reactivity Properties of the Substitution by Different Halogens on the Conjugated Backbone of the 1,3,5-triaryl-2-pyrazoline Skeleton in Relation to the Increasing Alkyloxy Chain Length: A Conceptual Density Functional Theory Study

  Norma Flores-Holguín, Asghar Abbas, Daniel Glossman-Mitnik
  JOURNAL OF MOLECULAR MODELING, Vol.26. No.174. pp1-12 (2020)

• Theoretical Modifications of the Molecular Structure of Aurantinidin and Betanidin Dyes to Improve their Efficiency as Dye Sensitized Solar Cells

  Aanuoluwapo Raphael Obasuyi, Daniel Glossman-Mitnik, Norma Flores-Holguín
  JOURNAL OF COMPUTATIONAL ELECTRONICS, Vol.19. No.2. pp507-515 (2020)

• A Fast and Simple Evaluation of the Chemical Reactivity Properties of the Pristinamycin Family of Antimicrobial Peptides

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  CHEMICAL PHYSICS LETTERS, Vol.739. No.137021. pp1-5 (2020)

• Conceptual DFT as a Novel Chemoinformatics Tool for Studying the Chemical Reactivity Properties of the Amatoxin Family of Fungal Peptides

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  OPEN CHEMISTRY, Vol.17. No.. pp1133-1139 (2019)

• Computational Study of the Chemical Reactivity and Bioactivity Rates of Marine Peptides Hemiasterlin and Its A and B Derivatives Used in the Cancer Treatment through Conceptual Density Functional Theory

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  Computational Molecular Bioscience, Vol.9. No.. pp95-107 (2019)

• Computational Study of the Chemical Reactivity and Bioactivity Rates of Marine Peptides Hemiasterlin and its A and B Derivatives Used in the Cancer Treatment through Conceptual Density Functional Theory

  Norma Flores-Holguín, Juan Frau and Daniel Glossman-Mitnik
  SIN REVISTA, Vol.9. No.4. pp95-107 (2019)

• Chemical Reactivity Properties, Solubilities, and Bioactivity Scores of Some Pigments Derived from Carotenoids of Marine Origin through Conceptual DFT Descriptors

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  JOURNAL OF CHEMISTRY, Vol.2019. No.9624108. pp12 (2019)

• Chemical Reactivity Properties, Drug-Likeness and Bioactivity Scores of the Seragamides A-F Anticancer Marine Peptides: The Conceptual DFT Viewpoint

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  Computation, Vol.7. No.52. pp1-13 (2019)

• Calculation of the Global and Local Conceptual DFT Indices for the Prediction of the Chemical Reactivity Properties of Papuamides A-F Marine Drugs

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  MOLECULES, Vol.24. No.18. pp3312 (2019)

• Tamoxifen-Loaded Nanodiamonds as a Potential Nanosystem for Drug Delivery to Breast Cancer Cells

  Loya-Rivera Mario, Garcia-Ruiz Sara C., Flores-Holguín, Norma, Orrantia-Borunda Erasmo, Chávez-Flores David, Luna-Velasco Antonia
  NANOSCIENCE AND NANOTECHNOLOGY LETTERS, Vol.11. No.8. pp1131-1138 (2019)

• Chemical Reactivity and Bioactivity Properties of the Phallotoxin Family of Fungal Peptides Based on Conceptual Peptidology and DFT Study

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  Heliyon, Vol.5. No.e02335. pp1-6 (2019)

• CDFT-Based Reactivity Descriptors as a Useful MEDT Chemoinformatics Tool for the Study of the Virotoxin Family of Fungal Peptides

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  MOLECULES, Vol.24. No.2707. pp1-10 (2019)

• Computational Peptidology Assisted by Conceptual DFT for the Study of Five New Antifungal Tripeptides

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  ACS OMEGA, Vol.4. No.1. pp12555-12560 (2019)

• Conceptual DFT as a Chemoinformatics Tool for the Study of the Taltobulin Anticancer Peptide

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  BMC Research Notes, Vol.12. No.442. pp1-4 (2019)

• Chemical Reactivity Properties, Drug-likeness Features and Bioactivity Scores of the Cholecystokinin Peptide Hormone

  Norma Flores-Holguín, Juan Frau and Daniel Glossman-Mitnik
  SIN REVISTA, Vol.9. No.2. pp41-47 (2019)

• Chemical Reactivity Properties, Drug-Likeness Features and Bioactivity Scores of the Cholecystokinin Peptide Hormone

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  Computational Molecular Bioscience, Vol.9. No.. pp41-47 (2019)

• THEORETICAL ANALYSIS OF THE ARRANGEMENT IN ZINC-PORPHYRINS DERIVATIVES AND ITS EFFECT IN THE ELECTRONIC PROPERTIES.

  NORA-AYDEE SANCHEZ-BOJORGE, Gerardo Zaragoza-Galán, Norma R Flores-Holguín, Marco Antonio Chávez-Rojo, César Castro-García, Luz Rodriguez-Valdez
  JOURNAL OF MOLECULAR STRUCTURE, Vol.1191. No.1. pp259-270 (2019)

• ANALYSIS OF THE INTERACTIONS BETWEEN CYTOCHROME P450 3A4 AND 1A2 WITH AFLATOXINS. A MOLECULAR DOCKING STUDY

  Isui Abril García Montoya, Norma Rosario Flores Holguín, Linda-Lucila Landeros-Martínez, Mónica Alvarado Gonzalez, Quintín Rascón Cruz, Pedro Palomares Báez y Luz Maria Rodriguez-Valdez
  Applied Sciences, Vol.9 . No.1. pp2467 (2019)

• Theoretical and Experimental Study of Different Chemical Routes to Synthesize Crystalline Sodium Metasilicate from Silica-Rich Sand

  A. Tejeda-Ochoa, C. Carreño-Gallardo, J.E. Ledezma-Sillas, C. Prieto-Gomez, N.R. Flores-Holguin, F.C. Robles-Hernandez, J.M. Herrera-Ramirez
  REVISTA MEXICANA DE INGENIERIA QUIMICA, Vol.18. No.2. pp581-588 (2019)

• Computational Prediction of Bioactivity Scores and Chemical Reactivity Properties of the Parasin I Therapeutic Peptide of Marine Origin Through the Calculation of Global and Local Conceptual DFT Descriptors

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  THEORETICAL CHEMISTRY ACCOUNTS, Vol.138. No.78. pp1-9 (2019)

• A proposal based on quantum phenomena for the ORR mechanism on nitrogen-doped carbon-based electrocatalysts

  A Legarreta-Mendoza, N Flores-Holguín, D Lardizabal-Gutiérrez
  INTERNATIONAL JOURNAL OF HYDROGEN ENERGY, Vol.44. No.24. pp12374/12380 (2019)

• Preparation, Spectroscopic Investigations and Chemical Reactivity Properties of a New Schiff Base Ligand and its Copper (II) Complexes

  Shiva Prasad Kollur, Joaquín Ortega Castro, Juan Frau, Norma Flores-Holguín, Govindaraju Shruthi, Chandan Shivamallu, Daniel Glossman-Mitnik
  JOURNAL OF MOLECULAR STRUCTURE, Vol.1191. No.. pp17-23 (2019)

• Electron Injection in Anthocyanidin and Betalain Dyes for Dye‐Sensitized Solar Cells: A DFT Approach

  Aanuoluwapo Raphael Obasuyi, Daniel Glossman‐Mitnik, Norma Flores‐Holguín
  JOURNAL OF COMPUTATIONAL ELECTRONICS, Vol.18. No.. pp396-406 (2019)

• A Comparison of Conceptual DFT and Molecular Electron Density Theory (MEDT) Descriptors of Local Chemical Reactivity Properties: Oxytocin and Vasopressin Peptide Hormones as Test Cases

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  SIN REVISTA, Vol.3. No.2. pp45-49 (2019)

• A Comparison of Conceptual DFT and Molecular Electron Density Theory (MEDT) Descriptors of Local Chemical Reactivity Properties: Oxytocin and Vasopressin Peptide Hormones as Test Cases

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  MOJ Bioorganic & Organic Chemistry, Vol.3. No.2. pp45-49 (2019)

• Chemical Reactivity Properties of Standard Aromatic Amino Acids Studied by Means of Conceptual Density Functional Theory

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  SIN REVISTA, Vol.4. No.1. pp1-10 (2019)

• Chemical Reactivity Properties of Standard Aromatic Amino Acids Studied by Means of Conceptual Density Functional Theory

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  SOJ Biochemistry, Vol.. No.. pp (2019)

• Chemical Reactivity Theory and Empirical Bioactivity Scores as Computational Peptidology Alternative Tools for the Study of Two Anticancer Peptides of Marine Origin

  Juan Frau, Norma Flores-Holguín, Daniel Glossman-Mitnik
  MOLECULES, Vol.24. No.6. pp1115 (2019)

• Conceptual Density Functional Theory Study of the Chemical Reactivity Properties and Bioactivity Scores of the Leu-Enkephalin Opioid Peptide Neurotransmitter

  Juan Frau, Norma Flores-Holguín and Daniel Glossman-Mitnik
  SIN REVISTA, Vol.9. No.1. pp16-23 (2019)

• Conceptual Density Functional Theory Study of the Chemical Reactivity Properties and Bioactivity Scores of the Leu-Enkephalin Opioid Peptide Neurotransmitter

  Juan Frau, Norma Flores-Holguín, Daniel Glossman-Mitnik
  Computational Molecular Bioscience, Vol.9. No.1. pp13-26 (2019)

• An Alternative Approach to Computational Peptidology Based on Conceptual DFT and Empirical Bioactivity Scores

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  MEDICINAL CHEMISTRY, Vol.9. No.3. pp27-30 (2019)

Libros

• Computational Chemistry Study of Natural Apocarotenoids and their Synthetic Glycopeptide Conjugates as Therapeutic Drugs

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  IntechOpen, 2022 Reino Unido, ISBN:ISBN: 978-1-80355-424-2, Print ISBN: 978-1-80355-423-5, EBook (PDF) ISBN: 978-1-80355-425-9

• Evaluation of Annona muricata Acetogenins as Potential Anti-SARS-CoV-2 Agents Through Computational Approaches

  Shashanka K Prasad, Sushma Pradeep, Chandan Shimavallu, Shiva Prasad Kollur, Asad Syed, Najat Marraiki, Chukwuebuka Egbuna, Mihnea-Alexandru Gaman, Olga Kosakowska, William C. Cho, Kingsley Chukwuemeka Patrick-Iwuanyanwu, Joaquín Ortega Castro, Juan Frau, Norma Flores-Holguín, Daniel Glossman-Mitnik
  Frontiers Media SA, 2021 Suiza, ISBN:978-2-88971-872-6

• Determination of Chemical Reactivities of Oxytocin and Vasopressin Peptide Hormones Studied through Conceptual Density Functional Theory (CDFT) and Molecular Electron Density Theory (MEDT)

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  Book Publisher International, 2021 India, ISBN:ISBN: 978-93-91882-28-0 (Print), ISBN: 978-93-91882-38-9 (eBook)

• About the Computational Prediction of the Maximum Absorption Wavelengths of Indigo in Different Solvents with the Minnesota Family of Density Functionals

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  Book Publishers International, 2021 India, ISBN:ISBN 978-93-91473-81-5 (Print) ISBN 978-93-91473-88-4 (eBook)

• Study on the Molecular Reactivity of the Dansylglycine in Water and Dioxane Estimated through Conceptual DFT

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  Book Publishers International, 2021 India, ISBN:ISBN 978-93-91473-81-5 (Print) ISBN 978-93-91473-88-4 (eBook)

• Determining the Informatics and Conceptual DFT Study of Pigments Derived from Carotenoids of Marine Origin

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  Book Publishers International, 2021 India, ISBN:ISBN 978-93-91473-81-5 (Print) ISBN 978-93-91473-88-4 (eBook)

• Revisiting the Validation of the KID Methodology through CDFT Descriptors of Fluorescent DNA Staining Dyes

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  Book Publisher International, 2021 Reino Unido, ISBN:Print ISBN: 978-93-91312-07-7, eBook ISBN: 978-93-91312-12-1

• Study on the Computational Nutraceutics of a Citrus Flavonoid: An Approach Using Conceptual Density Functional Theory (CDFT)

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  Book Publishers International, 2021 India, ISBN:ISBN 978-93-91473-81-5 (Print) ISBN 978-93-91473-88-4 (eBook)

• Repurposing Drugs for the Inhibition of Advanced Glycation Inhibition: A Computational Study of the Chemical Reactivity Properties of the Met-Enkephalin Neurotransmitter Peptide by Means of Conceptual DFT

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  Nova Science Publishers, Inc, 2021 Estados Unidos de América, ISBN:978-1-53619-176-9

• Conceptual DFT as a Chemoinformatics Tool for the Study of the Clavanin Family of Antimicrobial Marine Peptides

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  IntechOpen, 2021 Reino Unido, ISBN:978-1-83881-083-2

• Chemical Reactivity Properties and Bioactivity Scores of the Angiotensin II Vasoconstrictor Octapeptide

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  IntechOpen, 2020 Reino Unido, ISBN:978-1-83962-518-3

• Conceptual DFT as a Novel Chemoinformatics Tool for Studying the Chemical Reactivity Properties of the Amatoxin Family of Fungal Peptides

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  Vide Leaf, 2020 India, ISBN:978-93-90014-08-8

• CDFT-Based Reactivity Descriptors as a Useful MEDT Chemoinformatics Tool for the Study of the Virotoxin Family of Fungal Peptides

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  Vide Leaf, 2020 India, ISBN:978-81-945175-2-8

• A Combined Molecular Docking and Electronic Structure Study for a Breast Cancer Drug Design

  Linda Lucila Landeros-Martínez, Daniel Glossman-Mitnik, Erasmo Orrantia-Borunda, Norma Flores-Holguín
  IntechOpen, 2018 Reino Unido, ISBN:Print ISBN 978-1-78923-354-4 - Online ISBN 978-1-78923-355-1 - eBook (PDF) ISBN 978-1-83881-432-8

• Assessment of the Validity of Some Minnesota Density Functionals for the Prediction of the Chemical Reactivity of the SYBR Green I and Ethidium Bromide Nucleic Acid Stains

  Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
  InTech, 2018 México, ISBN:978-1-78923-133-5

Reconocimientos y Distinciones

• Segundo lugar en el concurso "Premio al Proyecto Innovador de Negocios Verdes"

  Instituto Global para la Sostenibilidad del Tecnológico de Monterrey

• Reconocimiento al artículo Density functional theory (DFT) study of triphenylamine-based dyes for their use as sensitizers in molecular photovoltaics.Baldenebro-López J, Castorena-González J, Flores-Holguín N, Almaral-Sánchez J, Glossman-Mitnik D: I

  BioMedLib Journal

• Evaluadores Acreditados (RCEA)

  CONACYT (RCEA)

• Investigador nacional Nivel 1

  Sistema Nacional de Investigadores SNI (CONACYT)

• Reconocimiento al artículo THEOCHEM 905, Issue 1-3, (2009) 76-80 como "Top 25 Hottest Articles"

  Elsevier Science

• Reconocimiento al artículo THEOCHEM 854 (2008) 81-88 como "Top 25 Hottest Articles"

  Elsevier Science